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    Angiotensin Ii Receptor Blockers At Work

    Angiotensin II Receptor Blockers or simply called ARB is one among anti-hypertensive agents like ACE inhibitors that alleviate high blood pressure by dilating the blood vessels. Angiotensin II is a chemical component found usually in blood vessels that is responsible for the contraction of its walls. This contraction outcomes to narrowing of the blood vessels and this narrowing promote high blood pressure. Angiotensin II receptor blockers work by preventing the performance of angiotensin II. When there is less activity of angiotensin II, there is also an easy flow of blood in the vessels thereby lowering the occurrence of hypertension.

    The only difference between angiotensin II receptor blockers and ACE inhibitors is that the former prevents the action of the angiotensin II while the latter prohibits the formation or production of angiotensin II.

    Aside from regulating blood pressure by blood vessel widening, angiotensin II receptor blockers are used as treatment for heart failure, kidney failure in patients with hypertension and diabetes. Since they work the same with ACE inhibitors, angiotensin II receptor blockers are often used as substitutes when ACE inhibitors do not become effective. ARBs are also applied as medication on scleroderma patients.

    Angiotensin II receptor blockers are mostly accepted by patients of hypertension. The the bulk common side effects though are coughing, increase in potassium levels, low blood pressure, faintness, headache, diarrhea, metallic or salty taste, rashes, nasal congestion, back and leg pain. Adverse but rare effects of ARBs are liver failure, kidney failure, alleviated white blood cells and tissue swelling called angioedema.

    Before taking this medication worries that may influence treatment including interaction with other drug should be given attention. It is better to discuss with doctors about your allergies, as this may be worsened by the presence of angiotensin II receptor blockers in your system. The patient must report to the doctor if he has history of allergic intolerance of previously taken anti-hypertensive drugs. Allergies to food dyes and preservatives may make you sensitive to ARBs.

    Inform the doctor if the patient is in her family way. Drugs like angiotensin II receptor blockers are not perfect for pregnancy as it may cause unknown birth defects.

    Elder patients who are allergic to alpha-blockers (one type of anti-hypertensive drug) are more often than not sensitive to ARBs.

    Common angiotensin II receptor blockers found in stores are the following:

    * Valsartan - starting does 80 mg or 160 mg once everyday
    * Irebsartan - starting dose is 50 mg once daily
    * Candesartan - ordinary dose is 4-32 mg once daily
    * Losartan - starting dose is 50 mg once daily

    Observing proper dosage and taking ARBs at the prescribed time will aid the patient achieve a desirable blood pressure.

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